![]() ![]() Anyone who has skipped their regular morning cup is familiar with a caffeine headache. In these people, the relationship between caffeine and migraine is actually a negative one.Ĭaffeine withdrawal hurts. People who are more sensitive to caffeine appear to be more vulnerable to it contributing to an attack. It means that for some, caffeine is quickly processed out of the bloodstream, but for others, it lingers longer. If you’ve ever taken a home genetic test, you may have seen we have a genetic marker for the body’s ability to metabolize caffeine (the genes XYP1A2 and AHR). Some people tolerate caffeine better than others. Studies have shown that adding caffeine to other pain medicines decreases the dose of the pain medicine required to achieve pain relief. It increases the activity of acetaminophen and aspirin in the body and decreases their clearance, so they work longer on treating pain. Between stopping pain and allowing more dopamine to flow, it’s no wonder caffeine helps to relieve head pain.Ĭaffeine also helps other pain medicines work better. In addition, when adenosine is blocked, the brain chemical dopamine becomes more plentiful–– which gives us a feeling of pleasure. Caffeine inhibits adenosine from doing its job. Adenosine is a neurotransmitter, which promotes pain and inflammation in the brain. Even a cup of coffee can reduce head pain.Ĭaffeine inhibits adenosine receptors in the brain. Painkillers with caffeine (Anacin, Excedrin Migraine, Excedrin Extra Strength, Vanquish) are remarkably effective as quick-fixes. Studies have found that doses of 200 mg can help reduce tension-type and migraine headaches. Caffeine And Migraine: The Stimulant That Helps Pain Go AwayĬaffeine has well-known pain-relieving properties. Is caffeine okay or not for people with migraine? Let’s take a closer look at the relationship between caffeine and migraine. How can both of these things be true at the same time? For those of us who perk up around the aroma of freshly-brewed coffee, these contradictions might leave us confused. Yet, caffeine––or the lack of it––can also trigger a headache. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.Fact: Caffeine can relieve migraine and make pain medicine work more effectively. Portions of this document last updated: Feb. You may report side effects to the FDA at 1-80. If you notice any other effects, check with your healthcare professional.Ĭall your doctor for medical advice about side effects. Other side effects not listed may also occur in some patients. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Some side effects may occur that usually do not need medical attention. Get emergency help immediately if any of the following symptoms of overdose occur: Symptoms of overdose Vomiting of blood or material that looks like coffee grounds Check with your doctor immediately if any of the following side effects occur: More commonīurning feeling or tenderness in the stomach
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